Topographic analysis of the macupapillary posterior pole in patients with mild alzheimer's disease
Abstract
The aim of this transversal study was to perform a topographic analysis of the macula and the temporal papillary region of the retina and to relate it with the changes seen in the macular and peripapillary retinal thickness in a group of patients with mild Alzheimer’s disease (AD) compared with control. Macular and peripapillary thickness were measured by optical coherence tomography (OCT). It was found a significant macular and peripapillary thinning in some sectors in mild AD patients in comparison with control group, getting a map that revealed the earlier areas affected in AD. Therefore, this finding point to those regions in the macular and papillary region of the retina that could be useful as early biomarker for follow-up in AD.
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